The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 10, 2021

Filed:

May. 30, 2017
Applicant:

Ottawa Heart Institute Research Corporation, Ottawa, CA;

Inventors:

Duncan J. Stewart, Ottawa, CA;

David Courtman, Ottawa, CA;

Seth Mount, Ottawa, CA;

Darryl Davis, Ottawa, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/34 (2015.01); C12N 5/077 (2010.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/34 (2013.01); A61K 9/0019 (2013.01); C12N 5/0657 (2013.01); C12N 2500/02 (2013.01); C12N 2500/38 (2013.01); C12N 2500/44 (2013.01); C12N 2500/62 (2013.01); C12N 2500/90 (2013.01); C12N 2500/98 (2013.01); C12N 2501/119 (2013.01); C12N 2501/155 (2013.01); C12N 2533/52 (2013.01);
Abstract

Methods for generating serum-free and/or xenogen-free cardiac explant-derived stem cells (EDC) are provided. These methods may include providing an initial cardiac explant, which has been minced and digested; plating the initial cardiac explant; culturing the plated cardiac explant in serum-free and xenogen-free medium; harvesting EDC cells surrounding or emerging from the plated cardiac explant; and optionally performing static expansion of harvested EDC cells in serum-free and xenogen-free media. Serum-free and/or xenogen-free cardiac EDC cells produced by these methods, as well as methods and uses thereof for the treatment of heart failure in a subject in need thereof, are also provided.


Find Patent Forward Citations

Stewart, Duncan. (2021). Serum-free and xenogen-free human cardiac explant-derived stem cells and uses and methods for the production thereof (U.S. Patent No. 11083756). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11083756

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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