The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2021
Filed:
Sep. 12, 2018
Oxford Nanopore Technologies Ltd., Oxford, GB;
Lakmal Jayasinghe, Oxford, GB;
John Hagan Pryce Bayley, Oxford, GB;
Stephen Cheley, East Lansing, MI (US);
Brian McKeown, Middle Barton Oxon, GB;
James White, Oxford, GB;
James Anthony Clarke, Oxford, GB;
Oxford Nanopore Technologies Ltd., Oxford, GB;
Abstract
The invention relates to constructs comprising a transmembrane protein pore subunit and a nucleic acid handling enzyme. The pore subunit is covalently attached to the enzyme such that both the subunit and enzyme retain their activity. The constructs can be used to generate transmembrane protein pores having a nucleic acid handling enzyme attached thereto. Such pores are particularly useful for sequencing nucleic acids. The enzyme handles the nucleic acid in such a way that the pore can detect its component nucleotides by stochastic sensing.