The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2021
Filed:
Jun. 09, 2016
Macrogenics, Inc., Rockville, MD (US);
Jon Marc Wigginton, Rockville, MD (US);
Naimish Bharat Pandya, Clarksville, MD (US);
Robert Joseph Lechleider, Bethesda, MD (US);
Scott Koenig, Rockville, MD (US);
Ezio Bonvini, Potomac, MD (US);
MacroGenics, Inc., Rockville, MD (US);
Abstract
This invention relates to a pharmaceutical composition that comprises a first molecule that specifically binds HER2/neu and a second molecule that specifically binds a cell-surface receptor (or its ligand) that is involved in regulating an immune checkpoint (or the ligand thereof). The invention particularly relates to the embodiment wherein the second molecule binds to PD-1. The invention also relates to the use of such pharmaceutical compositions to treat cancer and other diseases.