The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 03, 2021

Filed:

Apr. 30, 2007
Applicants:

Patrick M. Hughes, Aliso Viejo, CA (US);

Gerald W. Devries, Laguna Hills, CA (US);

Robert T. Lyons, Laguna Hills, CA (US);

John T. Trogden, Anaheim, CA (US);

Scott M. Whitcup, Laguna Hills, CA (US);

Inventors:

Patrick M. Hughes, Aliso Viejo, CA (US);

Gerald W. DeVries, Laguna Hills, CA (US);

Robert T. Lyons, Laguna Hills, CA (US);

John T. Trogden, Anaheim, CA (US);

Scott M. Whitcup, Laguna Hills, CA (US);

Assignee:

ALLERGAN, INC., Irvine, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); A61K 47/34 (2017.01); A61K 38/39 (2006.01); A61K 9/00 (2006.01); C12N 15/113 (2010.01); A61K 9/08 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 9/0048 (2013.01); A61K 9/08 (2013.01); A61K 38/39 (2013.01); A61K 47/34 (2013.01); C12N 15/1138 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/317 (2013.01); C12N 2310/332 (2013.01); C12N 2320/32 (2013.01);
Abstract

Anti-angiogenesis compositions, and methods of using such compositions, useful for injection into the vitreous of human eyes are provided. Such compositions include MAAC solutions or particles present in a therapeutically effective amount, a viscosity-inducing component, and an aqueous carrier component. The compositions have viscosities at about 25° C. of at least about 10 cps or about 100 cps at a shear rate of 0.1/second. In a preferred embodiment, the viscosity at 25° C. is in the range of from about 80,000 cps to about 300,000 cps.


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