The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2021
Filed:
Aug. 26, 2019
Applicant:
Symthera Canada Ltd., Ontario, CA;
Inventor:
Chai Ezerzer, Ness Ziona, IL;
Assignee:
SYMTHERA CANADA LTD., Toronto, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/71 (2006.01); C07K 14/47 (2006.01); G01N 33/74 (2006.01); C07K 14/485 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); C07K 14/47 (2013.01); C07K 14/485 (2013.01); G01N 33/74 (2013.01); C07K 2319/00 (2013.01); G01N 2333/485 (2013.01); G01N 2333/49 (2013.01);
Abstract
Disclosed are binding agents that include (a) a calcium binding portion which includes an F-helix peptide and a calcium binding loop peptide derived from an EF-hand motif of a calcium binding protein, wherein the C-terminus of the F-helix peptide is covalently linked to the N-terminus of the calcium binding loop peptide by a peptide bond, and (b) a targeting peptide, wherein the N-terminus of the targeting peptide is covalently linked to the C-terminus of the calcium binding portion by a peptide bond. The binding agents can be used for diagnosis and treatment of various disorders.