The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2021
Filed:
Aug. 26, 2016
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Loren D. Walensky, Newton, MA (US);
Gregory H. Bird, Pelham, NH (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 14/47 (2006.01); A61K 47/54 (2017.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); C12Q 1/6886 (2018.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4747 (2013.01); A61K 38/1761 (2013.01); A61K 45/06 (2013.01); A61K 47/545 (2017.08); A61P 35/00 (2018.01); C12Q 1/6886 (2013.01); A61K 38/00 (2013.01); C12Q 2600/106 (2013.01);
Abstract
This disclosure features stapled peptide inhibitors (e.g., cysteine-reactive stapled peptides) of the anti-apoptotic protein, BFL-1, and methods of using same in the treatment of BFL-1 expressing cancers.