The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 03, 2021

Filed:

Sep. 29, 2017
Applicant:

University of Florida Research Foundation, Incorporated, Gainesville, FL (US);

Inventors:

Mavis Agbandje-McKenna, Gainesville, FL (US);

Mario Mietzsch, Gainesville, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12N 15/00 (2006.01); C07K 14/005 (2006.01); C12N 15/86 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); C12N 15/86 (2013.01); C12N 2015/8518 (2013.01); C12N 2750/14122 (2013.01); C12N 2750/14143 (2013.01);
Abstract

This disclosure relates to variant AAVrh.10 particles engineered to escape host neutralizing antibodies but retain or improve transduction efficiency, and their use as gene delivery vehicles.


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