The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2021
Filed:
Dec. 11, 2017
Applicant:
Glaxosmithkline Intellectual Property Development Limited, Brentford, GB;
Inventors:
James Francis Callahan, King of Prussia, PA (US);
Vincent J. Colandrea, King of Prussia, PA (US);
Anthony William James Cooper, Stevenage, GB;
Nicole Cathleen Goodwin, King of Prussia, PA (US);
Chelsea Ariane Huff, King of Prussia, PA (US);
Joel Karpiak, King of Prussia, PA (US);
Jeffrey K. Kerns, King of Prussia, PA (US);
Hong Nie, King of Prussia, PA (US);
Assignee:
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED, Brentford, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/554 (2006.01); A61K 31/553 (2006.01); A61P 1/16 (2006.01); A61P 9/00 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 13/12 (2006.01); A61P 17/06 (2006.01); A61P 35/00 (2006.01); C07D 281/02 (2006.01); C07D 417/06 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 419/06 (2006.01); C07D 419/12 (2006.01); C07D 419/14 (2006.01); C07D 513/04 (2006.01); C07D 515/04 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 515/04 (2013.01); C07D 401/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 513/04 (2013.01);
Abstract
The present invention relates to bisaryl amide analogs, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the invention relates to bisaryl heterocycles of Formula (I),