The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2021
Filed:
Jul. 12, 2018
Applicant:
Ogeda SA, Anderlecht, BE;
Inventor:
Hamid Hoveyda, Brussels, BE;
Assignee:
Ogeda SA, Anderlecht, BE;
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61P 5/08 (2006.01); A61P 5/24 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 5/08 (2018.01); A61P 5/24 (2018.01); C07B 2200/05 (2013.01);
Abstract
Deuterated fezolinetant (R)-(4-fluorophenyl)-(8-methyl-3-(3-(methyl-d3)-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]trizolo[4,3-a]pyrazin-7(8H)-yl)methanone: or a pharmaceutically acceptable salt or solvate thereof, as an NK-3 antagonist. Also, methods of modulating NK-3 receptor activity including administering an effective amount of the compound or pharmaceutically acceptable salt or solvate thereof. Additionally, a process for manufacturing the compound or pharmaceutically acceptable salt or solvate thereof.