The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2021
Filed:
Jul. 04, 2017
Applicant:
Guangzhou Maxinovel Pharmaceuticals Co., Ltd., Guangzhou, CN;
Inventors:
Yuguang Wang, Guangdong, CN;
Zusheng Xu, Guangdong, CN;
Tianzhi Wu, Guangdong, CN;
Min He, Guangdong, CN;
Nong Zhang, Guangdong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/10 (2006.01); C07D 405/04 (2006.01); C07D 207/08 (2006.01); C07D 211/60 (2006.01); C07D 213/38 (2006.01); C07D 213/48 (2006.01); C07D 231/10 (2006.01); C07D 231/12 (2006.01); C07D 319/18 (2006.01); A61P 35/00 (2006.01); C07C 22/04 (2006.01); C07C 22/08 (2006.01); C07C 25/24 (2006.01); C07C 43/225 (2006.01); C07C 47/548 (2006.01); C07C 47/55 (2006.01); C07C 47/575 (2006.01); C07C 69/94 (2006.01); C07C 215/10 (2006.01); C07C 217/58 (2006.01); C07C 229/22 (2006.01); C07C 229/24 (2006.01); C07C 229/64 (2006.01); C07C 233/18 (2006.01); C07C 235/84 (2006.01); C07C 237/30 (2006.01); C07C 255/56 (2006.01);
U.S. Cl.
CPC ...
C07D 405/10 (2013.01); A61P 35/00 (2018.01); C07C 22/04 (2013.01); C07C 22/08 (2013.01); C07C 25/24 (2013.01); C07C 43/225 (2013.01); C07C 47/548 (2013.01); C07C 47/55 (2013.01); C07C 47/575 (2013.01); C07C 69/94 (2013.01); C07C 215/10 (2013.01); C07C 217/58 (2013.01); C07C 229/22 (2013.01); C07C 229/24 (2013.01); C07C 229/64 (2013.01); C07C 233/18 (2013.01); C07C 235/84 (2013.01); C07C 237/30 (2013.01); C07C 255/56 (2013.01); C07D 207/08 (2013.01); C07D 211/60 (2013.01); C07D 213/38 (2013.01); C07D 213/48 (2013.01); C07D 231/10 (2013.01); C07D 231/12 (2013.01); C07D 319/18 (2013.01); C07D 405/04 (2013.01); C07B 2200/07 (2013.01);
Abstract
Disclosed are an aromatic acetylene or aromatic ethylene compound, an intermediate, a preparation method, a pharmaceutical composition and a use thereof. The aromatic acetylene or aromatic ethylene compound has a significant inhibitory effect on PD-1 and PD-L1, and can effectively relieve or treat cancers and other related diseases.