The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 03, 2021

Filed:

Jul. 20, 2018
Applicant:

Reviral Limited, Stevenage, GB;

Inventors:

Stuart George Cockerill, Stevenage, GB;

James Good, Stevenage, GB;

Assignee:

REVIRAL LIMITED, Stevenage, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/06 (2006.01); C07D 413/14 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01); A61P 11/06 (2006.01); C07D 409/14 (2006.01); A61K 45/06 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/06 (2013.01); A61P 11/06 (2018.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); A61K 45/06 (2013.01);
Abstract

Benzimidazole derivatives of formula (I): wherein: Ris —(CH)m-Ror Ris halo, —(CH)—NHor —(CH)—C(═NH)—NH; Ris H or F; Ris —NH—(CH)—(NH)—R, —NH—(CHRR) or a group of the following formula (A): (A) W is —(CH)—, —CH—O—CH—, —CH—S—CH—, —(CH)—S(O)—CH— or —(CH)—NR—CH—; m is an integer of 1 to 3; n is 1 or 2; p is 1 and V is CH; or p is O and V is N; q is 0 or 1; r is 0 or 1; Ris H, —SOMe, —SOEt, —SOCF, —COMe, —CONMe, —CONHor —CHCHSOMe; Ris H or C-Calkyl; and Ris —SOMe, —SOEt, —SOCF, —COMe, —CONMe, —CONHor —CHCHSOMe; and the pharmaceutically acceptable salts thereof are inhibitors of RSV and can therefore be used to treat or prevent an RSV infection.


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