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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11078166 B1

PDFFull Text
Date of Patent:
Aug. 03, 2021

Filed:

Aug. 15, 2016

Triazole conjugated ureas, thioureas, carbamates, and reversed carbamates for psma-targeted imaging agents and uses thereof

Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Martin G. Pomper, Baltimore, MD (US);

Ying Chen, Lutherville-Timonium, MD (US);

Xing Yang, Baltimore, MD (US);

Ronnie C. Mease, Fairfax, VA (US);

Sangeeta Ray, Ellicott City, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorneys:

Casimir Jones, S.C.

Jeffrey W. Childers

Primary Examiner:

James W Rogers

Int. Cl.
CPC ...
C07D 249/04 (2006.01); A61K 51/04 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 249/04 (2013.01); A61K 51/0402 (2013.01); A61K 51/0453 (2013.01); C07B 59/002 (2013.01); A61K 2123/00 (2013.01); C07B 2200/05 (2013.01);
Abstract

Triazole conjugated urea-based and thiourea-based scaffolds that have high binding affinity to PSMA are disclosed. These scaffolds can be radiolabeled and used to image cells and tumors that express PSMA. Methods of synthesizing radiofluorinated triazole conjugated urea-based and thiourea-based scaffolds also are disclosed.

Find Patent Forward Citations

Pomper, Martin. (2021). Triazole conjugated ureas, thioureas, carbamates, and reversed carbamates for psma-targeted imaging agents and uses thereof (U.S. Patent No. 11078166). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11078166

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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