The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2021
Filed:
Feb. 15, 2018
Applicants:
Nanyang Technological University, Singapore, SG;
National University of Singapore, Singapore, SG;
Inventors:
Gerhard Grüber, Singapore, SG;
Roderick Wayland Bates, Singapore, SG;
Adam Hotra, Singapore, SG;
Thomas Dick, Singapore, SG;
Kevin Pethe, Singapore, SG;
Assignees:
NANYANG TECHNOLOGICAL UNIVERSITY, Singapore, SG;
NATIONAL UNIVERSITY OF SINGAPORE, Singapore, SG;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); C07D 239/48 (2006.01); A61P 31/06 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
C07D 239/48 (2013.01); A61K 31/437 (2013.01); A61K 31/47 (2013.01); A61P 31/06 (2018.01);
Abstract
The present invention relates to pyrimidine compounds and compositions for treating tuberculosis. These compounds may be used to target the Fdomain of F-ATP synthase and may be used with bedaquiline or 6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide (Q203) or a combination thereof.