The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 03, 2021

Filed:

Dec. 30, 2014
Applicants:

Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;

Universite Paris Diderot—paris 7, Paris, FR;

Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;

Universita Di Perugia, Perugia, IT;

American University of Beirut, Beirut, LB;

Assistance Publique-hopitaux DE Paris (Aphp), Paris, FR;

Inventors:

Hugues De The, Paris, FR;

Ali Bazarbachi, Beirut, LB;

Hiba El Hajj, Beirut, LB;

Maria Paula Martelli, Perugia, IT;

Brunangelo Falini, Perugia, IT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 33/36 (2006.01); A61K 31/203 (2006.01); A61K 31/555 (2006.01);
U.S. Cl.
CPC ...
A61K 33/36 (2013.01); A61K 31/203 (2013.01); A61K 31/555 (2013.01);
Abstract

The present invention relates to methods and pharmaceutical compositions for the treatment of acute myeloid leukemia. In particular, the present invention relates to a method for treating NPM-1-driven acute myeloid leukemia (AML) in a subject in need thereof comprising administering the subject with a therapeutically effective amount of at least one arsenic compound and with a therapeutically effective amount of at least one retinoid.


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