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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11077104 B1

PDFFull Text
Date of Patent:
Aug. 03, 2021

Filed:

Sep. 06, 2018

Pharmaceutical compositions comprising poh derivatives

Applicant:

Neonc Technologies, Inc., Los Angeles, CA;

Inventors:

Thomas Chen, La Canada, CA (US);

Daniel Levin, La Canada, CA (US);

Satish Pupalli, Rancho Cucamonga, CA (US);

Assignee:

NeOnc Technologies, Inc., Los Angeles, CA (US);

Attorney:

Leason Ellis LLP

Primary Examiner:

Taina D Matos Negron

Int. Cl.
CPC ...
A61K 31/495 (2006.01); A61K 31/415 (2006.01); A61K 47/54 (2017.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01); C07D 207/26 (2006.01); C07D 231/12 (2006.01); C07D 487/04 (2006.01); A61K 31/4188 (2006.01); A61K 31/045 (2006.01); A61K 31/4015 (2006.01); C07B 59/00 (2006.01); C07C 33/14 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/495 (2013.01); A61K 9/0043 (2013.01); A61K 31/045 (2013.01); A61K 31/4015 (2013.01); A61K 31/415 (2013.01); A61K 31/4188 (2013.01); A61K 45/06 (2013.01); A61K 47/54 (2017.08); A61K 47/542 (2017.08); A61K 47/543 (2017.08); A61N 5/10 (2013.01); C07B 59/00 (2013.01); C07C 33/14 (2013.01); C07D 207/26 (2013.01); C07D 231/12 (2013.01); C07D 487/04 (2013.01); C07B 2200/05 (2013.01); C07C 2601/16 (2017.05);
Abstract

The present invention provides for a derivative of monoterpene or sesquiterpene, such as a perillyl alcohol derivative. For example, the perillyl alcohol derivative may be a perillyl alcohol carbamate. The perillyl alcohol derivative may be perillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The present invention also provides for a method of treating a disease such as cancer, comprising the step of delivering to a patient a therapeutically effective amount of a derivative of monoterpene (or sesquiterpene). The route of administration may vary, and can include, inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection.

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