The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2021
Filed:
Aug. 09, 2019
Applicant:
Aptinyx Inc., Evanston, IL (US);
Inventors:
John A. Lowe, III, Stonington, CT (US);
M. Amin Khan, Evanston, IL (US);
Assignee:
Aptinyx Inc., Evanston, IL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/397 (2006.01); C07D 487/10 (2006.01); A61K 31/407 (2006.01);
U.S. Cl.
CPC ...
A61K 31/407 (2013.01); A61K 31/397 (2013.01); C07D 487/10 (2013.01);
Abstract
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.