The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2021

Filed:

Jul. 11, 2016
Applicant:

Dnae Group Holdings Limited, London, GB;

Inventors:

Sergey A. Dryga, Albuquerque, NM (US);

Victor C. Esch, Albuquerque, NM (US);

Richard G. Saul, Gaithersburg, MD (US);

Andrew F. McDowell, Albuquerque, NM (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/569 (2006.01); C07K 16/12 (2006.01); C12Q 1/689 (2018.01);
U.S. Cl.
CPC ...
G01N 33/54326 (2013.01); G01N 33/54333 (2013.01); G01N 33/56911 (2013.01); B01L 2200/0647 (2013.01); B01L 2400/043 (2013.01); C07K 16/1267 (2013.01); C12Q 1/689 (2013.01); G01N 2333/195 (2013.01); G01N 2446/20 (2013.01);
Abstract

The invention generally relates to using magnetic particles and alternating magnet fields to separate a target analyte from a sample. In certain embodiments, methods of the invention involve contacting a sample with magnetic particles including first moieties specific for a target analyte, thereby forming target/particle complexes in the sample, flowing the sample through a channel including second moieties attached to at least one surface of the channel, applying alternating magnetic fields to the flowing sample to result in target/particle complexes being brought into proximity of the surface to bind the second moieties and unbound particles remaining free in the sample, binding the target/particle complexes to the second moieties, and washing away unbound particles and unbound analytes of the sample.


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