The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2021

Filed:

Feb. 01, 2017
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Fei Liu, Mountain View, CA (US);

Utkan Demirci, Stanford, CA (US);

Sanjiv Sam Gambhir, Stanford, CA (US);

Viswam S. Nair, Tampa, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); B01L 3/00 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5091 (2013.01); B01L 3/50273 (2013.01); B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); G01N 33/50 (2013.01); G01N 33/5005 (2013.01); G01N 33/5308 (2013.01); G01N 2800/52 (2013.01); G01N 2800/56 (2013.01);
Abstract

A device ('the ExoTIC device') for the isolation of extracellular vesicles from an extracellular vesicle-containing sample in which the sample is flowed through a membrane in a flow chamber to capture and purify the extracellular vesicles on the membrane. The extracellular vesicles may be washed and collected and utilized in any one of a number of ways including, but not limited to, identifying biomarkers of a disease, identifying the presence of a biomarker in a patient to determine whether a patient has a disease, and therapeutically treating existing diseases by re-introducing the extracellular vesicles, potentially modified, back into a body.


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