The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 27, 2021
Filed:
Jul. 06, 2018
Fundacio Institut DE Recerca Biomedica (Irb Barcelona), Barcelona, ES;
Institucio Catalana DE Recerca I Estudis Avancats, Barcelona, ES;
Roger Gomis, Barcelona, ES;
Maria Tarragona, Barcelona, ES;
Anna Arnal, Barcelona, ES;
Milica Pavlovic, Lajkovac, RS;
FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA), Barcelona, ES;
INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS, Barcelona, ES;
Abstract
The present invention relates to a method for the diagnosis or the prognosis of metastasis in breast cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in ER− breast cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF gene expression level. Finally, the invention relates to the use of a c-MAF inhibitor as therapeutic target for treating the ER− breast cancer metastasis.