The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2021

Filed:

Oct. 06, 2015
Applicants:

The Johns Hopkins University, Baltimore, MD (US);

Umc Utrecht Holding B.v., Utrecht, NL;

Inventors:

Zachary Kaminsky, Baltimore, MD (US);

Marco Paul Maria Boks, Utrecht, NL;

Assignees:

The Johns Hopkins University, Baltimore, MD (US);

UMC UTRECHT HOLDING B.V., Utrecht, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C07H 21/04 (2006.01); C12Q 1/6883 (2018.01); G01N 33/92 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); G01N 33/92 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/156 (2013.01); G01N 2800/28 (2013.01); G01N 2800/301 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01); G01N 2800/7004 (2013.01);
Abstract

The present invention relates to the field of biomarkers. More specifically, the present invention relates to the use of biomarkers to predict post-traumatic stress disorder (PTSD). In one embodiment, a method for predicting PTSD in a subject comprises the steps of (a) measuring the DNA methylation level of a CpG dinucleotide in the 3' untranslated region of SKA2; (b) identifying the genotype at a SNP within the 3′ UTR of SKA2, and (c) predicting PTSD in the subject using a prediction algorithm.


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