The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2021

Filed:

Jan. 04, 2019
Applicant:

Quantum-si Incorporated, Guilford, CT (US);

Inventors:

Guojun Chen, Sherborn, MA (US);

Jeremy Lackey, Guilford, CT (US);

Alexander Goryaynov, New Haven, CT (US);

Gerard Schmid, Guilford, CT (US);

Ali Kabiri, Madison, CT (US);

Jonathan M. Rothberg, Guilford, CT (US);

Todd Rearick, Cheshire, CT (US);

Jonathan C. Schultz, Guilford, CT (US);

Farshid Ghasemi, Guilford, CT (US);

Keith G. Fife, Palo Alto, CA (US);

Assignee:

Quantum-Si Incorporated, Guilford, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6869 (2018.01); G01N 21/64 (2006.01); B01L 3/00 (2006.01); G01N 30/86 (2006.01); C08L 1/02 (2006.01); C12Q 1/6806 (2018.01); G01N 27/447 (2006.01); G01N 30/88 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); B01L 3/50857 (2013.01); B01L 3/502761 (2013.01); C08L 1/02 (2013.01); C12Q 1/6806 (2013.01); G01N 21/6428 (2013.01); G01N 21/6454 (2013.01); G01N 27/44743 (2013.01); G01N 27/44782 (2013.01); G01N 30/86 (2013.01); B01L 2200/0647 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0421 (2013.01); G01N 27/447 (2013.01); G01N 30/88 (2013.01);
Abstract

Apparatus and techniques for electrokinetic loading of samples of interest into sub-micron-scale reaction chambers are described. Embodiments include an integrated device and related apparatus for analyzing samples in parallel. The integrated device may include at least one reaction chamber formed through a surface of the integrated device and configured to receive a sample of interest, such as a molecule of nucleic acid. The integrated device may further include electrodes patterned adjacent to the reaction chamber that produce one or more electric fields that assist loading the sample into the reaction chamber. The apparatus may further include a sample reservoir having a fluid seal with the surface of the integrated device and configured to hold a suspension containing the samples.


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