The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2021

Filed:

Oct. 03, 2017
Applicant:

Juno Therapeutics, Inc., Seattle, WA (US);

Inventors:

James Sissons, Seattle, WA (US);

Cameron Brandt, Seattle, WA (US);

Alexandra Croft, Seattle, WA (US);

Allen Ebens, Seattle, WA (US);

Haley Peper, Seattle, WA (US);

Dean Y. Toy, Seattle, WA (US);

Assignee:

Juno Therapeutics, Inc., Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 16/28 (2006.01); C07K 14/725 (2006.01); C07K 16/08 (2006.01); A61P 31/20 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2833 (2013.01); A61K 39/12 (2013.01); A61P 31/20 (2018.01); C07K 14/7051 (2013.01); C07K 16/084 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/572 (2013.01); A61K 2039/585 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/32 (2013.01); C07K 2317/34 (2013.01); C07K 2317/622 (2013.01); C07K 2317/624 (2013.01); C07K 2319/02 (2013.01);
Abstract

Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.


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