The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 27, 2021
Filed:
Nov. 09, 2015
Allogene Therapeutics, Inc., South San Francisco, CA (US);
Cellectis, Paris, FR;
Arvind Rajpal, San Francisco, CA (US);
Shobha Chowdary Potluri, Foster City, CA (US);
Laurent Poirot, Paris, FR;
Alexandre Juillerat, New York, NY (US);
Thomas Charles Pertel, San Mateo, CA (US);
Donna Marie Stone, Brisbane, CA (US);
Barbra Johnson Sasu, San Francisco, CA (US);
Allogene Therapeutics, Inc., South San Francisco, CA (US);
Cellectis, Paris, FR;
Abstract
The invention relates to an inhibitory chimeric antigen receptor (N-CAR) comprising an extracellular domain comprising an antigen binding domain, a transmembrane domain, and, an intracellular domain wherein the intracellular domain comprises an Immunoreceptor Tyrosine-based Switch Motif ITSM, wherein said ITSM is a sequence of amino acid TXYXXX, wherein Xis an amino acid Xis an amino acid Xis an amino acid and Xis V or I.