The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 27, 2021
Filed:
Nov. 14, 2016
Zealand Pharma A/s, Søborg, DK;
Universite DE Montreal, Montreal, CA;
Manuel Perez Vazquez, Milton, CA;
M. Monzur Morshed, Mississauga, CA;
Jennifer L. Hickey, Toronto, CA;
Adam Paul Kafal, Toronto, CA;
James Gillard, Rosemere, CA;
Narendra Patel, Brampton, CA;
Sai Kumar Chakka, Brampton, CA;
Andrew L. Roughton, Port Hope, CA;
Marc-André Poupart, Laval, CA;
Gaoqiang Yang, Montreal, CA;
Universite de Montreal, Montreal, CA;
Zealand Pharma A/S, Søborg, DK;
Abstract
There is described herein antagonists of α4β7 integrin, and more particularly to cyclic peptide antagonists. Accordingly, there is described herein a compound of formula (I) wherein R, R, R, R, R, R, Rand Rare various substituents; stereocentres 1*, 2* and 3* are each independently selected from R and S; n is 1, 2, 3, or 4 and where n is 2-4, Z is an amino terminus of an amino acid; —C═O— adjacent L is the carboxy terminus of an amino acid; and L along with Z and —C═O— is a peptide.