The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2021

Filed:

Sep. 17, 2018
Applicants:

Shanghai Synergy Pharmaceutical Sciences Co., Ltd., Shanghai, CN;

Zhejiang Huahai Pharmaceutical Co., Ltd., Linhai, CN;

Inventors:

Xin Xu, Shanghai, CN;

Zhen Zhang, Shanghai, CN;

Yunfei Li, Shanghai, CN;

Liming Zhang, Shanghai, CN;

Fengying Guo, Shanghai, CN;

Qingyun Jiang, Shanghai, CN;

Dongsheng Li, Shanghai, CN;

Linli Zhang, Shanghai, CN;

Jinqian Song, Shanghai, CN;

Lei Liu, Shanghai, CN;

Qiang Liu, Shanghai, CN;

Jing Su, Shanghai, CN;

Yijin Wang, Shanghai, CN;

Jian Ge, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/04 (2006.01); C07D 405/14 (2006.01); C07D 495/04 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 417/14 (2013.01); C07D 495/04 (2013.01);
Abstract

Disclosed are a class of μ-opioid receptor agonists and a preparation method therefor and the use thereof in the field of medicine, belonging to the field of medicinal chemistry. The μ-opioid receptor agonists significantly increase the selectivity for a G protein signaling pathway, and not only can exhibit excellent pharmacodynamic effects, but also significantly improve safety.


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