The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2021

Filed:

Jun. 14, 2018
Applicant:

Selection Bioscience Llc, Shanghai, CN;

Inventors:

Fuyao Zhang, Shanghai, CN;

Hongshun Yuan, Shanghai, CN;

Xiaoming Shen, Shanghai, CN;

Assignee:

SELECTION BIOSCIENCE LLC, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/10 (2006.01); A61P 35/00 (2006.01); C07B 59/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/10 (2013.01); A61P 35/00 (2018.01); C07B 59/002 (2013.01); A61K 45/06 (2013.01);
Abstract

Disclosed are a compound as shown in general formula I, a pharmaceutically acceptable salt, an isomer or a mixture thereof, and a solvate, a polymorph, a stable isotope derivative or a prodrug thereof. The compound of the present disclosure has comparatively strong PARP inhibitory activity and can be used for treating diseases associated with PARP, such as cancers and inflammatory diseases.


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