The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 27, 2021
Filed:
Jun. 20, 2016
Bayer Pharma Aktiengesellschaft, Berlin, DE;
Hans-Georg Lerchen, Leverkusen, DE;
Anne-Sophie Rebstock, Champagne au Mont d'Or, FR;
Yolanda Cancho Grande, Leverkusen, DE;
Sven Wittrock, Berlin, DE;
Sandra Berndt, Hohen Neuendorf, DE;
Uwe Gritzan, Cologne, DE;
Jenny Fitting, Cologne, DE;
Beatrix Stelte-Ludwig, Wülfrath, DE;
Patrick Jones, Oakland, CA (US);
Christoph Mahlert, Wuppertal, DE;
Christian Votsmeier, Cologne, DE;
Dorian Schönfeld, Cologne, DE;
Mark Trautwein, Whippany, NJ (US);
Ernst Weber, Langenfeld, DE;
Nikolaus Pawlowski, Cologne, DE;
Simone Greven, Dormagen, DE;
Julian Marius Glück, Meerbusch, DE;
Stefanie Hammer, Berlin, DE;
Lisa Dietz, Wuppertal, DE;
Stephan Märsch, Cologne, DE;
BAYER PHARMA AKTIENGESELLSCHAFT, Berlin, DE;
Abstract
The present application relates to novel binder drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prophylaxis of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.