The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 27, 2021

Filed:

Jun. 16, 2017
Applicant:

Children's Medical Center Corporation, Boston, MA (US);

Inventors:

Paula I. Watnick, Waban, MA (US);

Szu Yu Liao, Boston, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); C07K 14/28 (2006.01); C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
A61K 39/107 (2013.01); C07K 14/28 (2013.01); C12N 1/20 (2013.01); A61K 39/39 (2013.01); A61K 2039/522 (2013.01); A61K 2039/542 (2013.01); A61K 2039/55544 (2013.01);
Abstract

Some aspects of this disclosure provide engineered exopolysaccharide-associated proteins, engineered bacteria expressing such proteins, and engineered biofilms comprising such proteins. Some aspects of this disclosure provide methods for engineering exopolysaccharide-associated proteins, and for the generation of engineered bacteria and biofilms expressing or comprising such proteins. Some aspects of this disclosure provide compositions and methods useful for the generation of vaccines and the vaccination of subjects, for delivering molecules of interest to a target site, for example, a surface, for purification of molecules of interest, for example, from bioreactors comprising engineered bacteria as provided herein, and for bioremediation applications, such as the cleanup of environmental pollutants.


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