The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Nov. 24, 2015
Adaptive Biotechnologies Corporation, Seattle, WA (US);
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Harlan S. Robins, Seattle, WA (US);
William Sumner DeWitt, III, Seattle, WA (US);
Ryan O. Emerson, Seattle, WA (US);
Adaptive Biotechnologies Corporation, Seattle, WA (US);
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Abstract
Methods of monitoring and measuring dynamic adaptive immune cell responses are provided. High-throughput sequencing of T cell receptor and immunoglobulin loci is used to characterize the breadth of an effector cell response to a stimulus, such as a vaccine or infection. Unique responding effector cell clones and abundance thereof can be determined. Additionally, methods for determining the contribution of responding effector cells to the immunological memory compartment are provided.