The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 20, 2021

Filed:

Jan. 11, 2017
Applicant:

Quantapore, Inc., Menlo Park, CA (US);

Inventors:

Daniel Koslover, Menlo Park, CA (US);

Brett N. Anderson, Menlo Park, CA (US);

Assignee:

Quantapore, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6869 (2018.01); G01N 21/64 (2006.01); G01N 33/487 (2006.01); G01N 33/48 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); G01N 21/6408 (2013.01); G01N 21/6428 (2013.01); G01N 33/48 (2013.01); G01N 33/48721 (2013.01); G01N 2021/6432 (2013.01); G01N 2021/6441 (2013.01);
Abstract

The invention is directed to nanopore arrays comprising opaque layers that reduce background fluorescence in optical signal collected in applications of such arrays for analyzing molecules. In some embodiments, such arrays are used to determine characteristics of polymers, such as polynucleotides, in methods comprising the steps of translocating polymers through nanopores of such arrays wherein polymers have one or more optical labels, exciting optical labels of the polymers in a signal generation region of each nanopore extending from the opaque layer toward the direction of the excitation beam, detecting optical signals from the signal generation regions of each nanopore to determine characteristics of the polymer translocating therethrough.


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