The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Jul. 22, 2016
The Regents of the University of California, Oakland, CA (US);
Pfizer Inc., New York, NY (US);
Thomas Mikita, Sausalito, CA (US);
Lauren K. Ely, Palo Alto, CA (US);
Huilan Gao, West Roxbury, MA (US);
Yun Kim, Walnut Creek, CA (US);
Isaac J. Rondon, San Francisco, CA (US);
Tovo David, San Francisco, CA (US);
Shaun R. Coughlin, Tiburon, CA (US);
The Regents of the University of California, Oakland, CA (US);
Pfizer, Inc., New York, NY (US);
Abstract
In one aspect, antibodies, or antigen-binding fragments thereof, that specifically bind to activated Factor XI (FXIa) are provided. Also provided are methods of obtaining such antibodies and nucleic acids encoding the same. In another aspect, compositions and therapeutic prevention of thrombotic diseases, disorders or conditions are provided. In another aspect, anti-idiotype antibodies that bind anti-FXIa antibodies of the disclosure, as well as compositions comprising the anti-idiotype antibodies, methods of obtaining the antibodies and nucleic acids encoding the same, are also provided.