The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Aug. 25, 2017
Applicant:
Oncotherapy Science, Inc., Kawasaki, JP;
Inventors:
Assignee:
ONCOTHERAPY SCIENCE, INC., Kawasaki, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/30 (2006.01); G01N 33/573 (2006.01); G01N 33/574 (2006.01); C07K 16/18 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 39/0011 (2013.01); C07K 16/18 (2013.01); C12N 15/85 (2013.01); G01N 33/573 (2013.01); G01N 33/57492 (2013.01); A61K 39/00118 (2018.08); A61K 39/001154 (2018.08); C12N 2015/8518 (2013.01); G01N 2800/364 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01);
Abstract
The present invention relates to monoclonal antibodies against MELK. Furthermore, the present invention provides methods for diagnosing MELK-associated diseases using the antibodies, methods for detecting the MELK protein, methods for determining the drug efficacy following treatment with a MELK inhibitor, methods of screening for subjects to whom a MELK inhibitor has a high therapeutic effect, and diagnostic reagents containing the antibodies.