The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Dec. 29, 2016
Applicant:
Kodiak Sciences Inc., Palo Alto, CA (US);
Inventors:
Daniel Victor Perlroth, Palo Alto, CA (US);
Wah Yuen To, San Mateo, CA (US);
Hong Liang, Hillsborough, CA (US);
Assignee:
KODIAK SCIENCES INC., Palo Alto, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); C07K 16/22 (2006.01); A61K 39/44 (2006.01); A61P 27/02 (2006.01); A61K 47/60 (2017.01); A61K 47/58 (2017.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 47/605 (2017.08); A61K 47/6845 (2017.08); C07K 2317/526 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
Provided herein are anti-VEGF-A antibodies and antibody conjugates thereof. Some embodiments of the antibodies can be conjugated to a moiety, such as a HEMA-PC polymer. Some embodiments of the antibody conjugates can retain or enhance antibody activity. The antibody and conjugate thereof can be particularly useful for treating diabetic retinopathy. Further provided are methods for conjugation of a polymer to a protein such as an antibody, such as IgG1.