The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 20, 2021

Filed:

May. 17, 2016
Applicant:

Universita′ Degli Studi Di Trento, Trento, IT;

Inventors:

Guido Grandi, Povo, IT;

Valeria Cafardi, Povo, IT;

Laura Fantappie′, Povo, IT;

Renata Grifantini, Siena, IT;

Alberto Grandi, Siena, IT;

Assignee:

BIOMVIS SRL, Siena, IT;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/095 (2006.01); A61K 39/102 (2006.01); A61K 39/108 (2006.01); C07K 14/22 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4748 (2013.01); A61K 39/0258 (2013.01); A61K 39/095 (2013.01); A61K 39/102 (2013.01); C07K 14/22 (2013.01); C07K 2319/40 (2013.01); G01N 2333/212 (2013.01); G01N 2333/22 (2013.01); G01N 2333/245 (2013.01);
Abstract

The present invention provides means and products for the stimulation of an immune response against tumors in a subject in need thereof. More specifically the invention provides immunogenic compositions containing bacterial outer membrane vesicles loaded with tumor antigens, fusion proteins comprising a bacterial protein and a tumor antigen, and isolated bacterial outer membrane vesicles (OMVs) containing said fusion proteins. The fusion proteins, OMVs and immunogenic compositions according to the invention are used in the prevention and treatment of tumors.


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