The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
May. 07, 2019
Applicant:
Buck Institute for Research on Aging, Novato, CA (US);
Inventors:
Barbara J. Bailus, Novato, CA (US);
Lisa M. Ellerby, San Anselmo, CA (US);
Assignee:
Buck Institute for Research on Aging, Novato, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/42 (2017.01); A61K 47/64 (2017.01); A61K 47/65 (2017.01); C07K 14/18 (2006.01); C07K 19/00 (2006.01); C07K 14/01 (2006.01); C12N 15/66 (2006.01); A61K 9/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/01 (2013.01); A61K 9/0085 (2013.01); A61K 47/42 (2013.01); A61K 47/64 (2017.08); A61K 47/65 (2017.08); C07K 14/1825 (2013.01); C12N 15/66 (2013.01); A61K 38/00 (2013.01); C07K 2319/33 (2013.01); C07K 2319/43 (2013.01); C07K 2319/50 (2013.01); C07K 2319/74 (2013.01); C07K 2319/80 (2013.01); C12N 2310/20 (2017.05);
Abstract
In various embodiments constructs are provided for the delivery of an effector molecule into a cell. In certain embodiments the construct comprises a cell penetrating peptide (CPP) attached to an effector that is to be delivered into a cell, where the cell penetrating peptide comprises a Zika cell penetrating peptide (Zika CPP), and the effector is selected from the group consisting of a protein, a nucleic acid, an organic compound, a nanoparticle, a viral particle, and the like.