The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Apr. 27, 2018
Applicant:
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);
Inventors:
Anthony B. Pinkerton, La Jolla, CA (US);
Robert J. Ardecky, La Jolla, CA (US);
Jiwen Zou, La Jolla, CA (US);
Assignee:
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 401/12 (2006.01); C07D 475/04 (2006.01); A61K 31/5377 (2006.01); A61K 31/4985 (2006.01); A61K 31/498 (2006.01); C07D 519/00 (2006.01); A61P 3/04 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61P 3/04 (2018.01); A61K 45/06 (2013.01);
Abstract
Protein tyrosine phosphatases (PTPs) are key regulators of metabolism and insulin signaling. As a negative regulator of insulin signaling, the low molecular weight protein tyrosine phosphatase (LMPTP) is a target for insulin resistance and related conditions. Described herein are compounds capable of modulating the level of activity of low molecular weight protein tyrosine phosphatase (LMPTP) and compositions, and methods of using these compounds and compositions.