The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Dec. 21, 2017
Applicant:
Frequency Therapeutics, Inc., Woburn, MA (US);
Inventors:
Christopher Loose, Winchester, MA (US);
Bradley Tait, North Andover, MA (US);
Rajesh Manchanda, Acton, MA (US);
Will Mclean, North Haven, CT (US);
Assignee:
Frequency Therapeutics, Inc., Woburn, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); A61K 9/00 (2006.01); C07D 487/04 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 9/0046 (2013.01); C07D 487/04 (2013.01); A61K 45/06 (2013.01);
Abstract
The present invention relates to 1H-pyrrole-2,5-dione compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into tissue cells.