The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Mar. 07, 2018
Applicant:
Guangzhou Maxinovel Pharmaceuticals Co., Ltd., Guangzhou, CN;
Inventors:
Assignee:
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD., Guangdong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/044 (2006.01); C07D 473/00 (2006.01); C07D 487/04 (2006.01); A61K 31/519 (2006.01);
U.S. Cl.
CPC ...
C07D 491/044 (2013.01); C07D 473/00 (2013.01); C07D 487/04 (2013.01);
Abstract
Disclosed in the present invention is an aminopyrimidine five-membered heterocyclic compound, and an intermediate, preparation method, pharmaceutical composition and application thereof. The aminopyrimidine five-membered heterocyclic compound provided by the present invention has a significant antagonistic effect on adenosine A2A receptors, and may be used as an antagonist for adenosine A2A receptors to effectively relieve or treat immune tolerance, diseases of the central nervous system, inflammatory diseases and like related diseases, while the preparation method is simple.