The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Sep. 06, 2016
Applicant:
Allegheny-singer Research Institute, Pittsburgh, PA (US);
Inventors:
Saadyah Averick, Pittsburgh, PA (US);
Ahmed Badr, Sewickley, PA (US);
Shaohua Li, Pittsburgh, PA (US);
Keith LeJeune, Export, PA (US);
Assignee:
Allegheny-Singer Research Institute, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/58 (2006.01); C07D 401/10 (2006.01); C07F 9/59 (2006.01); C07D 405/12 (2006.01); C07D 401/14 (2006.01); C07D 401/06 (2006.01);
U.S. Cl.
CPC ...
C07D 211/58 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); C07F 9/59 (2013.01);
Abstract
Various fentanyl derivatives are described. The derivatives exhibit high binding affinity to opioid receptors, but also have decreased blood brain permeability as compared to standard fentanyl. This, the resulting derivatives can be less addictive than standard fentanyl. Methods of making such derivatives are also disclosed in this document.