The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 20, 2021

Filed:

Oct. 02, 2017
Applicant:

King Abdullah University of Science and Technology, Thuwal, SA;

Inventors:

Shahad Alsaiari, Thuwal, SA;

Mohamed Amen Hammami, Thuwal, SA;

Niveen M. Khashab, Thuwal, SA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 47/62 (2017.01); A01N 25/26 (2006.01); A61K 31/7036 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6929 (2017.08); A01N 25/26 (2013.01); A61K 31/7036 (2013.01); A61K 47/62 (2017.08); A61K 47/6923 (2017.08); G01N 33/56955 (2013.01);
Abstract

Embodiments of the present disclosure describe a conjugate comprising a mesoporous nanoparticle having a plurality of pores, wherein the mesoporous nanoparticle is positively charged, wherein an active agent is disposed in the pore; and a plurality of metal nanoclusters, wherein the metal nanocluster has a negative charge, wherein a gate agent is attached to the metal nanocluster. Embodiments of the present disclosure also describe a method of using a conjugate comprising exposing a conjugate to microbes sufficient to release an active agent and treating the microbes with the released active agent. Embodiments of the present disclosure further describe a method of using a conjugate comprising exposing a conjugate to microbes and detecting a presence of the microbes.


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