The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 20, 2021

Filed:

Dec. 28, 2017
Applicant:

Intocell Inc., Daejeon, KR;

Inventors:

Tae Kyo Park, Daejeon, KR;

Sung Ho Woo, Daejeon, KR;

Sun Young Kim, Daejeon, KR;

Doo Hwan Jung, Daejeon, KR;

Sang Kwang Lee, Daejeon, KR;

Jong Un Cho, Daejeon, KR;

Jae Ho Lee, Sejong, KR;

Su Ho Park, Daejeon, KR;

Dong Hoon Seo, Daejeon, KR;

Hyang Sook Lee, Daejeon, KR;

Beom Seok Seo, Daejeon, KR;

Ji Yeon Lim, Daejeon, KR;

Assignee:

IntoCell Inc., Daejeon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 47/54 (2017.01); A61K 45/06 (2006.01); A61K 31/40 (2006.01); C07K 16/32 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
A61K 47/6889 (2017.08); A61K 31/40 (2013.01); A61K 45/06 (2013.01); A61K 47/549 (2017.08); A61K 47/6415 (2017.08); A61K 47/6801 (2017.08); A61K 47/6855 (2017.08); C07K 16/32 (2013.01); C07K 2317/24 (2013.01);
Abstract

The present invention relates to a compound bearing a self-immolative linker having β-galactoside-introduced thereto. In a compound bearing a β-galactoside-introduced self-immolative linker according to the present invention, particularly, the self-immolative linker may form a glycosidic bond with a protein (e.g., an oligopeptide, polypeptide, an antibody, etc.) or ligand which has specific affinity for a desired target or with an active agent (e.g., a drug, a toxin, a ligand, a detection probe, etc.), which has a specific function or activity so as to allow the selective release of the active agent within a target cell.


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