The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Dec. 14, 2016
Applicant:
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Inventors:
Eric M. Jeffries, West New York, NJ (US);
Yadong Wang, Bradford Woods, PA (US);
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/58 (2017.01); A61K 38/18 (2006.01); A61K 38/20 (2006.01); A61K 9/06 (2006.01); A61K 38/21 (2006.01); A61K 47/36 (2006.01); A61K 9/10 (2006.01); A61K 47/34 (2017.01); A61K 9/08 (2006.01); A61K 47/61 (2017.01); A61P 9/10 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 31/727 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/58 (2017.08); A61K 9/0019 (2013.01); A61K 9/06 (2013.01); A61K 9/08 (2013.01); A61K 9/10 (2013.01); A61K 31/727 (2013.01); A61K 38/18 (2013.01); A61K 38/1825 (2013.01); A61K 38/20 (2013.01); A61K 38/208 (2013.01); A61K 38/2066 (2013.01); A61K 38/21 (2013.01); A61K 47/34 (2013.01); A61K 47/36 (2013.01); A61K 47/61 (2017.08); A61P 9/10 (2018.01); A61P 35/00 (2018.01);
Abstract
Provided herein are coacervate compositions including cytokines, and methods of making and using the same. The coacervate can be formed by the mixing of an active agent, such as a drug or protein with the polyanion, such as heparin or heparan sulfate, and a custom-made polycation (e.g., PEAD or PELD). The coacervates can be used in the treatment of diseases and disorders where targeted treatment is desired, for example in treatment of cancers.