The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 20, 2021

Filed:

Apr. 11, 2017
Applicant:

Oxford University Innovation Limited, Oxfordshire, GB;

Inventors:

Adrian V. S. Hill, Oxfordshire, GB;

Anita Gola, Oxfordshire, GB;

Adam Walters, Oxfordshire, GB;

Alexandra Spencer, Oxfordshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/02 (2006.01); A61K 9/51 (2006.01); A61K 9/14 (2006.01); A61K 39/015 (2006.01); A61K 39/29 (2006.01); A61K 39/12 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01); A61K 39/235 (2006.01); A61K 39/275 (2006.01); A61K 39/245 (2006.01); A61K 39/285 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); A61K 39/12 (2013.01); A61K 39/29 (2013.01); C12N 7/00 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/57 (2013.01); A61K 2039/572 (2013.01); C12N 2710/10343 (2013.01); C12N 2710/24143 (2013.01); Y02A 50/30 (2018.01);
Abstract

The invention relates to a kit comprising at least a first composition and a second composition, each said first and second compositions comprising at least one epitope of a liver disease antigen, wherein said epitope is a CD8+T cell epitope, for use in induction of an immune response in the liver of a mammalian subject by administration of said first composition by intramuscular (i.m.), subcutaneous (s.c.), intradermal (i.d.) or aerosol route, and administration of said second composition by intravenous (i.v.) or subcutaneous (s.c.) route, characterised in that said first and second compositions are administered by different routes. The invention also relates to uses, methods and treatments.


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