The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 20, 2021

Filed:

Aug. 21, 2018
Applicants:

Duke University, Durham, NC (US);

Biomimetix Jv, Llc, Englewood, CO (US);

Inventors:

Ru-Rong Ji, Chapel Hill, NC (US);

Tong Liu, Durham, NC (US);

Ines Batinic-Haberle, Durham, NC (US);

David S. Warner, Chapel Hill, NC (US);

Kimberly C. Stone, Greenwood Village, CO (US);

James D. Crapo, Englewood, CO (US);

Assignees:

Duke University, Durham, NC (US);

BioMimetix JV, LLC, Englewood, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/555 (2006.01); A61K 31/4188 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/555 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 31/4188 (2013.01);
Abstract

A method of treating pruritus (itching) in a subject in need thereof is carried out by administering the subject an active agent in a treatment effective amount, wherein the active agent is a superoxide dismuate (SOD) mimetic. The SOD mimetic can be a complex of a metal (e.g., manganese) and an organic ligand, with suitable organic ligands including porphyrins, polyamines, salens, nitroxides, and fullerenes. Compositions for carrying out such methods are also described.


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