The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Oct. 26, 2018
Applicant:
Sonic Master Limited, Tortola, VG;
Inventors:
Amanda Rickard, San Diego, CA (US);
Uli Schmidt, San Diego, CA (US);
Alexander Kiselyov, San Diego, CA (US);
Assignee:
Sonic Master Limited, Tortola, VG;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4709 (2006.01); A61K 31/519 (2006.01); A61K 9/00 (2006.01); A61P 21/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4709 (2013.01); A61K 9/0053 (2013.01); A61K 31/519 (2013.01); A61P 21/00 (2018.01);
Abstract
Disclosed are methods and compositions for the treatment of facioscapulohumeral muscular dystrophy. In some cases, the methods and compositions involve the use of kinase inhibitors include Src, Syk, Abl, Tie, Flt, ErbB, Trk, PRKDC, and Yes families to repress DUX4 expression in muscle cells. Further disclosed are methods and cell based assays for screening compounds for the treatment of facioscapulohumeral muscular dystrophy.