The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 20, 2021

Filed:

May. 05, 2020
Applicant:

Recurium Ip Holdings, Llc, San Diego, CA (US);

Inventors:

Peter Qinhua Huang, San Diego, CA (US);

Deborah Helen Slee, Encinitas, CA (US);

Sayee Gajanan Hegde, San Diego, CA (US);

Chad Daniel Hopkins, San Diego, CA (US);

Kevin Duane Bunker, Escondido, CA (US);

Joseph Robert Pinchman, San Diego, CA (US);

Rakesh Kumar Sit, San Diego, CA (US);

Assignee:

Recurium IP Holdings, LLC, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); A61K 31/438 (2006.01); C07C 69/738 (2006.01); C07C 69/732 (2006.01); C07D 471/04 (2006.01); C07B 59/00 (2006.01); C07C 69/757 (2006.01); C07D 209/10 (2006.01); A61P 5/30 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/438 (2013.01); A61K 31/437 (2013.01); A61P 5/30 (2018.01); A61P 35/00 (2018.01); C07B 59/002 (2013.01); C07C 69/732 (2013.01); C07C 69/738 (2013.01); C07C 69/757 (2013.01); C07D 209/10 (2013.01); C07D 471/04 (2013.01); C07C 2603/62 (2017.05);
Abstract

Compounds of Formula (I) are estrogen receptor alpha modulators, where the variables in Formula (I) are described in the disclosure. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for treating diseases or conditions that are estrogen receptor alpha dependent and/or estrogen receptor alpha mediated, including conditions characterized by excessive cellular proliferation, such as breast cancer.


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