The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 20, 2021

Filed:

Nov. 07, 2019
Applicant:

Adamas Pharma, Llc, Emeryville, CA (US);

Inventors:

Gregory T. Went, San Francisco, CA (US);

Timothy J. Fultz, Big Canoe, GA (US);

Sangita Ghosh, Foster City, CA (US);

Natalie McClure, Portola Valley, CA (US);

Assignee:

Adamas Pharma, LLC, Emeryville, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/136 (2006.01); A61P 25/28 (2006.01); A61P 25/16 (2006.01); A61K 9/50 (2006.01); A61K 9/00 (2006.01); A61K 31/13 (2006.01);
U.S. Cl.
CPC ...
A61K 31/136 (2013.01); A61K 9/0053 (2013.01); A61K 9/501 (2013.01); A61K 9/5015 (2013.01); A61K 9/5026 (2013.01); A61K 9/5031 (2013.01); A61K 9/5042 (2013.01); A61K 9/5047 (2013.01); A61K 9/5078 (2013.01); A61K 31/13 (2013.01); A61P 25/16 (2018.01); A61P 25/28 (2018.01);
Abstract

Provided herein are oral pharmaceutical compositions comprising amantadine, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient, and which have a low level of organic solvent. Provided are also methods of orally administrating a composition comprising amantadine, or a pharmaceutically acceptable salt thereof, to a subject, which has reduced gastrointestinal side effects or sleep disturbances. Further provided are extended release oral compositions comprising amantadine, or a pharmaceutically acceptable salt thereof, that are suitable for once daily administration.


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