The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2021

Filed:

Mar. 23, 2020
Applicant:

Bruker Daltonik Gmbh, Bremen, DE;

Inventor:

Tobias Boskamp, Worpswede, DE;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01J 49/00 (2006.01); G16B 40/10 (2019.01); G01N 33/68 (2006.01); G01N 24/08 (2006.01); G01N 33/483 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 29/46 (2006.01);
U.S. Cl.
CPC ...
H01J 49/0036 (2013.01); G01N 24/087 (2013.01); G01N 29/46 (2013.01); G01N 33/4833 (2013.01); G01N 33/5008 (2013.01); G01N 33/53 (2013.01); G01N 33/6848 (2013.01); G16B 40/10 (2019.02); H01J 49/0004 (2013.01); H01J 49/0009 (2013.01); G01N 2223/423 (2013.01); G01N 2496/25 (2013.01);
Abstract

The disclosure relates to a method which is suitable for the quality control and signal correction of mass spectrometry data of biological tissue samples and is based on the analysis of the chemical background signal observed in a spectrum. It exploits the fact that the chemical background signal contains components from a plurality of polymer molecules, whose chemical structure has strong regularities. These regularities mean that the observed masses are subject to certain statistical distributions, which are each characteristic of the class of molecule. By analyzing these statistical properties, it is possible to detect and correct any mass shifts which may be present.


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