The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2021

Filed:

Apr. 07, 2017
Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Skolkovo Institute of Science and Technology, Moscow, RU;

The United States of America, As Represented By, the Secretary, Department of Health and Human Services, Bethesda, MD (US);

Inventors:

Konstantin Severinov, Piscataway, NJ (US);

Feng Zhang, Cambridge, MA (US);

Yuri I. Wolf, Bethesda, MD (US);

Sergey Shmakov, Moscow, RU;

Ekaterina Semenova, Piscataway, NJ (US);

Leonid Minakhin, Piscataway, NJ (US);

Kira S. Makarova, Bethesda, MD (US);

Eugene Koonin, Bethesda, MD (US);

Silvana Konermann, Zurich, CH;

Julia Joung, Boston, MA (US);

Jonathan S. Gootenberg, Cambridge, MA (US);

Omar O. Abudayyeh, Boston, MA (US);

Eric S. Lander, Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/90 (2006.01); C12N 15/10 (2006.01); C12N 15/63 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/82 (2006.01); C12N 15/85 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C12N 9/22 (2013.01); C12N 15/102 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/63 (2013.01); C12N 15/8201 (2013.01); C12N 15/85 (2013.01); C12N 2310/111 (2013.01); C12N 2310/20 (2017.05); C12N 2800/22 (2013.01);
Abstract

The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.


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