The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 2021
Filed:
May. 19, 2017
Applicant:
Larix Bioscience Llc, Sunnyvale, CA (US);
Inventors:
Bo Yu, San Jose, CA (US);
James Larrick, Woodside, CA (US);
Assignee:
Larix Bioscience LLC, Sunnyvale, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/67 (2006.01); C12N 15/79 (2006.01); C12N 15/113 (2010.01); C12N 15/10 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/102 (2013.01); C12N 15/113 (2013.01); C12N 15/67 (2013.01); C12N 15/79 (2013.01); C12N 15/907 (2013.01); C12N 15/1137 (2013.01); C12N 2310/20 (2017.05); C12Y 204/01068 (2013.01); C12Y 302/01018 (2013.01);
Abstract
The present invention provides a method and compositions utilizing the CRISPR system to disrupt a target gene in eukaryotic cells to produce double allele knock outs. The method finds use in producing afucosylated antibodies with enhanced ADCC activity.